2-Chloro-pyrimidin-4-carboxylic acid

2-Chloro-pyrimidin-4-carboxylic acid - Names and Identifiers

Name	2-Chloropyrimidine-4-carboxylic acid
Synonyms	AKOS BBS-00002507 CHEMBRDG-BB 4010944 4-Carboxy-2-chloropyrimidine 2-Chloropyrimidine-4-CarboxylicAci 2-Chloropyrimidine-4-carboxylicacid 2-Chloro-pyrimidin-4-carboxylic acid 2-Chloropyrimidine-4-carboxylic acid 4-Pyrimidinecarboxylic acid, 2-chloro- acide 2-chloropyrimidine-4-carboxylique 4-Carboxy-2-chloropyrimidine, 4-Carboxy-2-chloro-1,3-diazine
CAS	149849-92-3
InChI	InChI=1/C5H3ClN2O2/c6-5-7-2-1-3(8-5)4(9)10/h1-2H,(H,9,10)

2-Chloro-pyrimidin-4-carboxylic acid - Physico-chemical Properties

Molecular Formula	C5H3ClN2O2
Molar Mass	158.54
Density	1.579
Boling Point	411.4±18.0 °C(Predicted)
Flash Point	202.612°C
Vapor Presure	0mmHg at 25°C
Appearance	White to white-like solid
pKa	2.44±0.10(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.598

2-Chloro-pyrimidin-4-carboxylic acid - Risk and Safety

Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S22 - Do not breathe dust. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
HS Code	29335990
Hazard Class	IRRITANT

2-Chloro-pyrimidin-4-carboxylic acid - Introduction

Pyridinium, also known as 2-chloro-4-carboxylic acid pyridine, is an organic compound. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: acid is a white to light yellow solid powder.
-Solubility: Soluble in organic solvents such as ketones, ethers and alcohols, insoluble in water.
-Chemical properties: acid is a derivative of pyridine, which has the properties of pyridine and can participate in common organic reactions such as esterification, substitution reactions and electrophilic addition.

Use:
-Pharmaceutical industry: acid can be used as an intermediate for the synthesis of drugs. It plays an important role in the synthesis of many antibacterial drugs, antiviral drugs and anticancer drugs.
-Pesticide field: It can also be used as a raw material for pesticides, used in the production of pesticides and herbicides.

Method:
-or acid can be prepared by reacting pyridine with chloroformic acid in the presence of a base. The specific synthesis method is that pyridine is first dissolved in an alcohol solvent, then chloroformic acid is added, and then an alkali catalyst is added to perform the reaction. After the end of the reaction, the acid product is obtained by distillation or other separation methods.

Safety Information:
-acid is an organic compound with a certain degree of danger. Pay attention to personal protection during operation, avoid direct contact with skin and inhalation of dust.
-This compound may be irritating to the respiratory system, skin and eyes. Therefore, wear appropriate protective gloves, goggles and respiratory protection during operation.
-When storing or handling acid, keep it well ventilated to avoid contact with strong oxidants to avoid dangerous chemical reactions.

Please be sure to operate safely according to the specific situation and experimental conditions, and follow the safety manual and operating instructions of the relevant chemicals.

Last Update：2024-04-09 20:48:19